Two papers have recently been published by Petrocchi et al in Bioorg Med Chem Lett and Kettle et. al., in J Med Chem describing compounds which are potent and selective MTH1 inhibitors, the compounds bind to the MTH1 enzyme in cells but do not kill cancer cells. Both... read more
Sanjiv Kumar is one of the researchers who published an article in Cell Report about a new treatment for cancer. The new treatment is a combination of the two inhibitors. The inhibitors strike the respective proteins in the same signaling pathway. Today the two... read more
Congratulations to Paul L. Modrich, Tomas Lindahl and Aziz Sancar for receiving the Nobel prize in Chemistry 2015. We had the pleasure to meet Tomas Lindahl and talk with him about his work. The Swedish Nobel prize winner talked about his idols, background and his... read more
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