Two papers have recently been published by Petrocchi et al in Bioorg Med Chem Lett and Kettle et. al., in J Med Chem describing compounds which are potent and selective MTH1 inhibitors, the compounds bind to the MTH1 enzyme in cells but do not kill cancer cells. Both...
We are doing an AMA on Imgur with Thomas Helleday! Head on over there and ask him some questions! AMA with a...
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