Olga Loseva

Biologist

Published at Helleday Laboratory

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2016

Llona-Minguez, S; Hoglund, A; Jacques, S A; Johansson, L; Calderon-Montano, J M; Claesson, M; Loseva, O; Valerie, N C; Lundback, T; Piedrafita, J; Maga, G; Crespan, E; Meijer, L; Moron, Burgos E; Baranczewski, P; Hagbjork, A L; Svensson, R; Wiita, E; Almlof, I; Visnes, T; Jeppsson, F; Sigmundsson, K; Jensen, A J; Artursson, P; Jemth, A S; Stenmark, P; Berglund, Warpman U; Scobie, M; Helleday, T

Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1 Journal Article

J. Med. Chem., 59 (3), pp. 1140–1148, 2016, ([PubMed Central:hrefhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753678PMC4753678] [DOI:hrefhttp://dx.doi.org/10.1021/acs.jmedchem.5b0174110.1021/acs.jmedchem.5b01741] [PubMed:hrefhttp://www.ncbi.nlm.nih.gov/pubmed/2677166526771665]).

Abstract | BibTeX | Tags:

Reddy, P T; Jaruga, P; Nelson, B C; Lowenthal, M S; Jemth, A S; Loseva, O; Coskun, E; Helleday, T; Dizdaroglu, M

Production, Purification, and Characterization of (15)N-Labeled ĐNA Repair Proteins as Internal Standards for Mass Spectrometric Measurements Journal Article

Meth. Enzymol., 566 , pp. 305–332, 2016, ([DOI:hrefhttp://dx.doi.org/10.1016/bs.mie.2015.06.04410.1016/bs.mie.2015.06.044] [PubMed:hrefhttp://www.ncbi.nlm.nih.gov/pubmed/2679198526791985]).

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2015

Zhao, H; Sifakis, E G; Sumida, N; Millan-Arino, L; Scholz, B A; Svensson, J P; Chen, X; Ronnegren, A L; de Lima, Mallet C D; Varnoosfaderani, F S; Shi, C; Loseva, O; Yammine, S; Israelsson, M; Rathje, L S; Nemeti, B; Fredlund, E; Helleday, T; Imreh, M P; Gondor, A

PARP1- and CŦCF-Mediated Interactions between Active and Repressed Chromatin at the Lamina Promote Oscillating Ŧranscription Journal Article

Mol. Cell, 59 (6), pp. 984–997, 2015, ([DOI:hrefhttp://dx.doi.org/10.1016/j.molcel.2015.07.01910.1016/j.molcel.2015.07.019] [PubMed:hrefhttp://www.ncbi.nlm.nih.gov/pubmed/2632125526321255]).

Abstract | BibTeX | Tags:

Coskun, E; Jaruga, P; Jemth, A S; Loseva, O; Scanlan, L D; Tona, A; Lowenthal, M S; Helleday, T; Dizdaroglu, M

Addiction to MŦĦ1 protein results in intense expression in human breast cancer tissue as measured by liquid chromatography-isotope-dilution tandem mass spectrometry Journal Article

DNA Repair (Amst.), 33 , pp. 101–110, 2015, ([DOI:hrefhttp://dx.doi.org/10.1016/j.dnarep.2015.05.00810.1016/j.dnarep.2015.05.008] [PubMed:hrefhttp://www.ncbi.nlm.nih.gov/pubmed/2620234726202347]).

Abstract | BibTeX | Tags:

Palazzo, L; Thomas, B; Jemth, A S; Colby, T; Leidecker, O; Feijs, K L; Zaja, R; Loseva, O; Puigvert, J C; Matic, I; Helleday, T; Ahel, I

Processing of protein AĐP-ribosylation by Nudix hydrolases Journal Article

Biochem. J., 468 (2), pp. 293–301, 2015, ([DOI:hrefhttp://dx.doi.org/10.1042/BJ2014155410.1042/BJ20141554] [PubMed:hrefhttp://www.ncbi.nlm.nih.gov/pubmed/2578958225789582]).

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2014

Gad, H; Koolmeister, T; Jemth, A S; Eshtad, S; Jacques, S A; Strom, C E; Svensson, L M; Schultz, N; Lundback, T; Einarsdottir, B O; Saleh, A; Gokturk, C; Baranczewski, P; Svensson, R; Berntsson, R P; Gustafsson, R; Stromberg, K; Sanjiv, K; Jacques-Cordonnier, M C; Desroses, M; Gustavsson, A L; Olofsson, R; Johansson, F; Homan, E J; Loseva, O; Brautigam, L; Johansson, L; Hoglund, A; Hagenkort, A; Pham, T; Altun, M; Gaugaz, F Z; Vikingsson, S; Evers, B; Henriksson, M; Vallin, K S; Wallner, O A; Hammarstrom, L G; Wiita, E; Almlof, I; Kalderen, C; Axelsson, H; Djureinovic, T; Puigvert, J C; Haggblad, M; Jeppsson, F; Martens, U; Lundin, C; Lundgren, B; Granelli, I; Jensen, A J; Artursson, P; Nilsson, J A; Stenmark, P; Scobie, M; Berglund, U W; Helleday, T

MŦĦ1 inhibition eradicates cancer by preventing sanitation of the dNŦP pool Journal Article

Nature, 508 (7495), pp. 215–221, 2014, ([DOI:hrefhttp://dx.doi.org/10.1038/nature1318110.1038/nature13181] [PubMed:hrefhttp://www.ncbi.nlm.nih.gov/pubmed/2469522424695224]).

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2013

Al-Ubaidi, F L; Schultz, N; Loseva, O; Egevad, L; Granfors, T; Helleday, T

Castration therapy results in decreased Ku70 levels in prostate cancer Journal Article

Clin. Cancer Res., 19 (6), pp. 1547–1556, 2013, ([DOI:hrefhttp://dx.doi.org/10.1158/1078-0432.CCR-12-279510.1158/1078-0432.CCR-12-2795] [PubMed:hrefhttp://www.ncbi.nlm.nih.gov/pubmed/2334931623349316]).

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2011

Svensson, L M; Jemth, A S; Desroses, M; Loseva, O; Helleday, T; Hogbom, M; Stenmark, P

Crystal structure of human MŦĦ1 and the 8-oxo-dGMP product complex Journal Article

FEBS Lett., 585 (16), pp. 2617–2621, 2011, ([DOI:hrefhttp://dx.doi.org/10.1016/j.febslet.2011.07.01710.1016/j.febslet.2011.07.017] [PubMed:hrefhttp://www.ncbi.nlm.nih.gov/pubmed/2178777221787772]).

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2010

Loseva, O; Jemth, A S; Bryant, H E; Schuler, H; Lehtio, L; Karlberg, T; Helleday, T

PARP-3 is a mono-AĐP-ribosylase that activates PARP-1 in the absence of ĐNA Journal Article

J. Biol. Chem., 285 (11), pp. 8054–8060, 2010, ([PubMed Central:hrefhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832956PMC2832956] [DOI:hrefhttp://dx.doi.org/10.1074/jbc.M109.07783410.1074/jbc.M109.077834] [PubMed:hrefhttp://www.ncbi.nlm.nih.gov/pubmed/2006493820064938]).

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2009

Bryant, H E; Petermann, E; Schultz, N; Jemth, A S; Loseva, O; Issaeva, N; Johansson, F; Fernandez, S; McGlynn, P; Helleday, T

PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination Journal Article

EMBO J., 28 (17), pp. 2601–2615, 2009, ([PubMed Central:hrefhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738702PMC2738702] [DOI:hrefhttp://dx.doi.org/10.1038/emboj.2009.20610.1038/emboj.2009.206] [PubMed:hrefhttp://www.ncbi.nlm.nih.gov/pubmed/1962903519629035]).

Abstract | BibTeX | Tags:

Lehtio, L; Jemth, A S; Collins, R; Loseva, O; Johansson, A; Markova, N; Hammarstrom, M; Flores, A; Holmberg-Schiavone, L; Weigelt, J; Helleday, T; Schuler, H; Karlberg, T

Structural basis for inhibitor specificity in human poly(AĐP-ribose) polymerase-3 Journal Article

J. Med. Chem., 52 (9), pp. 3108–3111, 2009, ([DOI:hrefhttp://dx.doi.org/10.1021/jm900052j10.1021/jm900052j] [PubMed:hrefhttp://www.ncbi.nlm.nih.gov/pubmed/1935425519354255]).

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There are 2 major kinds of motorcycle chanel replica saddlebags. Throw over saddlebags and hard mount saddlebags. The concept of hard mount saddlebags originated from throw over saddlebags which were used in early 1950 for your first time. As the motorcycle business experienced a big boom in 1960 especially after the chanel replica sale the motorcycle luggage also evolved. As major motorcycle companies launched bigger and better motorcycle folks chanel replica sale began traveling farther on there motorcycles. Many riders formed groups and chanel replica rode cross country and from city to city. Chanel replica handbags outlet is your trusting choosing. This permanent installation resulted in the saddlebags is more reliable and sturdy.