Our vision is to find a cure for cancer
Many says that cancer is a too complex disease to be completely understood and cured. We think they are wrong.
50 years ago most children diagnosed with cancer succumbed, today most are cured. Testicular cancer was previously a death sentence, but is today in the vast majority of cases curable. Radio- and chemotherapy remain effective weapons for treating and in several cases also curing cancer.
Our idea is based on two strategies; DNA damage and combination treatments
DNA damage to kill cancers
Basically all potentially curative anti-cancer treatments work by causing DNA damage. With today’s detailed molecular knowledge of cell mechanism we are inventing more precise treatments than damaging radiation or strong chemical therapies.
In particular, cancers have high level of DNA damage caused by their differential metabolism. Our strategy is to convert cancer-specific damage into toxic lesions that will only cause damage to the cancer cells.
In the 1980’s people all over the world passed away in the AIDS epidemic, caused by the HIV virus. Since then the scientific community has seen the cure for AIDS as a scientific holy grail. Combination therapy became a winning tool and today effective treatments exist to prevent HIV carriers to develop AIDS, and a HIV diagnoses is no longer a death sentence.
Similarly, there is only a defined number of ways a cell can prevent or repair the DNA damage present in cancer cells. Our hypothesis is that with the right combination of DNA repair inhibitors cancer cells will be too damaged and stressed to continue to divide and multiply. As DNA damaging agents are able to sometimes cure cancer, we believe that the ultimate cure lay within the right combination strategy.