With a team of 70 scientists from 22 different nations we turn cancer defects into novel treatments. Subscribe to our newsletter to stay updated about our research!
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We proudly present a completely novel way of treating cancer, which has been published in Nature. The new concept exploits the high level of oxidative stress present within cancer that is absent in healthy cells. Oxidative stress can damage the building blocks of DNA, and the use of these damaged building blocks in DNA synthesis can cause cell death. The MTH1 protein protects cancer cells from this, and thus we aim to inhibit the MTH1 protein to specifically kill cancer cells.
“I am naturally happy and impressed by your work. Words can not describe how grateful I am; not only for my sake but for my children and family as well. It gives me hope to break the chain of cancer in the family. I hope for the drug to reach the market soon so more can be treated.” Translated from SwedishMarie
We turn cancer defects into novel treatments. Cancer cells already have a lot of DNA damage and disrupted DNA repair. By inhibiting DNA repair we increase the DNA damage to kill cancer cells, without harming healthy cells.