Congratulations Saeed Eshtad, PhD!

The Helleday lab wishes to congratulate Saeed Eshtad on a successful thesis defence on Monday February 13th! Saeeds’s thesis is called “Targeting DNA repair pathways for cancer therapy” and the aim of the thesis was to identify and understand if factors important in DNA repair of lesions caused by oxidative stress can be targeted to […]

Grattis Saeed Eshtad!

Ett stort grattis till nyblivne Fil.dr Saeed Eshtad som framgångsrikt disputerade med sin avhandling “ Targeting DNA repair pathways for cancer therapy” den 13 februari. Handledare till Saeed var Thomas Helleday och opponent var professor Arne Klungland från Oslo universitetssjukhus. Vill du läsa avhandlingen så finns den att hämta här. Fil.dr Saeed Eshtad och professor […]

Our metabolic target MTHFD2 crystal structure now resolved with inhibitor

The MTHFD2 protein is uniquely expressed in cancer and not in normal tissue. Yet, it is required for survival in cancer, but not for normal cells. This makes it a highly interesting target, with the potential of finding compounds that selectively kill cancer cells, but not normal cells. Key to success is to determine the […]